Leadership

  • Patricia Franklin, MD, MPH, MBA

    Patricia Franklin, MD, MPH, MBA
    Sr Scientific Director

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    Patricia Franklin, MD, MPH, MBA
    Sr Scientific Director

    For over two decades, Franklin's research has designed and implemented diverse methods to capture patient-reported health outcomes from national samples of patients, integrated these data with clinical and administrative data, and transformed data to real-world evidence. Longitudinal patient-reported data augment clinical data to create a learning health system integrating research, healthcare delivery, and quality improvement to improve health outcomes.

    Dr. Franklin currently serves as Professor of Medical Social Sciences and MPI for the K12 in Learning Health Systems at the Northwestern University Feinberg School of Medicine. Her career includes leadership in health system quality improvement as well as outcomes research. In the last decade, Dr. Franklin serves as Principal Investigator of the AHRQ P50; FORCE-TJR (2010-2015) for comparativeeffectiveness research in total joint replacement (TJR). The FORCE-TJR cohort includes 30,000 aging adults in 28 states with knee and hip osteoarthritis who report longitudinal pain and physical function. Early patient reported data (PROs) were collected on more than 80% of patients. Collection of 5-year outcomes was recently completed. A 2018 National Academy of Medicine report highlights FORCE-TJR as a patient-centered “learning health system” that supports federally funded ancillary research while serving quality initiatives for clinicians and health systems.

    Franklin's ongoing research includes tailored predictive outcome reports to inform shared decisions for knee and hip arthritis in a cluster randomized trial of 6000 patients (Franklin, PI; PCORI); predictive analytics of real-world physical therapy interventions to achieve optimal TJR outcomes (Franklin, PI; NIAMS R01); sociodemographic and geographic predictors of variation in TKR use (coI; NIAMS R01); pragmatic trial of comparative effectiveness of three anti-thrombotic medications in TJR (coI; PCORI); use of opioids following TJR (coI; NIAMS R01) and cultural adaptation of arthritis assessments for Vietnamese immigrants (coI; NIAMS R21).

  • David Ayers, MD

    David Ayers, MD
    Sr Orthopedic Director

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    David Ayers, MD
    Sr Orthopedic Director

    David Ayers is Arthur M. Pappas Professor of Orthopaedics, Chair of the Department of Orthopedics and Physical Rehabilitation, Medical Director of the Musculoskeletal Center of Excellence, as well as, Orthopedist-in-Chief at University of Massachusetts Memorial Health Care System in Worcester, MA. With Dr. Franklin, he led the development of several department-based clinical registries that uniquely include patient-reported outcomes in TJR, Spine, and Hand and upper extremity.

IT and Analytics

Data Collection and Management